Nurse practitioner salary in Missouri
The median nurse practitioner in Missouri earned $129,930 a year in 2025, $2,370 (2%) below the $132,300 national median. That ranks 35th of 51 states.
- Median yearly pay
- $129,930
- Average yearly pay
- $130,970
- Employed in Missouri
- 7,710
How Missouri compares
BLS Occupational Employment and Wage Statistics, May 2025, state estimates. Pay is before tax and does not adjust for cost of living, which is higher in some states than others.
Nursing pay in Missouri
| Role | Median yearly pay | Employed |
|---|---|---|
| Registered nurse | $81,780 | 76,310 |
| LPN or LVN | $61,530 | 14,700 |
| Nurse practitioner | $129,930 | 7,710 |
A nurse practitioner in Missouri earns a median $48,150 more than a registered nurse ($129,930 against $81,780). A registered nurse earns a median $20,250 more than an LPN or LVN here ($81,780 against $61,530).
Next steps
Common questions
How much does a nurse practitioner make in Missouri?
The median is $129,930 a year, according to BLS data for May 2025. Half of nurse practitioners in Missouri earn more and half earn less.
Is Missouri a high-paying state for nurse practitioners?
Missouri ranks 35th of 51 states on median pay for this job. The national median is $132,300, so Missouri pays 2% below it. The highest median is $168,520 in California.
How many nurse practitioners work in Missouri?
BLS counted 7,710 nurse practitioners employed in Missouri in May 2025.
Why is the average different from the median?
The median is the middle wage: half of workers earn less. The average adds every wage and divides, so a few very high earners pull it up. In Missouri the average is $130,970, $1,040 above the median.
What do you need to work as a nurse practitioner in Missouri?
Missouri requires an RN license plus a master’s or doctoral degree in an advanced practice specialty, and a state license.