Nurse practitioner salary in South Carolina
The median nurse practitioner in South Carolina earned $123,290 a year in 2025, $9,010 (7%) below the $132,300 national median. That ranks 48th of 51 states.
- Median yearly pay
- $123,290
- Average yearly pay
- $124,170
- Employed in South Carolina
- 5,670
How South Carolina compares
BLS Occupational Employment and Wage Statistics, May 2025, state estimates. Pay is before tax and does not adjust for cost of living, which is higher in some states than others.
Nursing pay in South Carolina
| Role | Median yearly pay | Employed |
|---|---|---|
| Registered nurse | $82,360 | 49,750 |
| LPN or LVN | $61,820 | 9,400 |
| Nurse practitioner | $123,290 | 5,670 |
A nurse practitioner in South Carolina earns a median $40,930 more than a registered nurse ($123,290 against $82,360). A registered nurse earns a median $20,540 more than an LPN or LVN here ($82,360 against $61,820).
Next steps
Common questions
How much does a nurse practitioner make in South Carolina?
The median is $123,290 a year, according to BLS data for May 2025. Half of nurse practitioners in South Carolina earn more and half earn less.
Is South Carolina a high-paying state for nurse practitioners?
South Carolina ranks 48th of 51 states on median pay for this job. The national median is $132,300, so South Carolina pays 7% below it. The highest median is $168,520 in California.
How many nurse practitioners work in South Carolina?
BLS counted 5,670 nurse practitioners employed in South Carolina in May 2025.
Why is the average different from the median?
The median is the middle wage: half of workers earn less. The average adds every wage and divides, so a few very high earners pull it up. In South Carolina the average is $124,170, $880 above the median.
What do you need to work as a nurse practitioner in South Carolina?
South Carolina requires an RN license plus a master’s or doctoral degree in an advanced practice specialty, and a state license.