Registered nurse salary in Mississippi

The median registered nurse in Mississippi earned $77,090 a year in 2025, $20,460 (21%) below the $97,550 national median. That ranks 50th of 51 states.

Median yearly pay
$77,090
Average yearly pay
$78,950
Employed in Mississippi
29,060

How Mississippi compares

  • California highest state$140,270
  • United States national median$97,550
  • Middle state median of state medians$93,600
  • Mississippi 50th of 51$77,090
  • Alabama lowest state$77,080

BLS Occupational Employment and Wage Statistics, May 2025, state estimates. Pay is before tax and does not adjust for cost of living, which is higher in some states than others.

Nursing pay in Mississippi

Median pay by nursing role in Mississippi
RoleMedian yearly payEmployed
Registered nurse$77,09029,060
LPN or LVN$50,2209,850
Nurse practitioner$124,7304,690

A nurse practitioner in Mississippi earns a median $47,640 more than a registered nurse ($124,730 against $77,090). A registered nurse earns a median $26,870 more than an LPN or LVN here ($77,090 against $50,220).

Next steps

Common questions

How much does a registered nurse make in Mississippi?

The median is $77,090 a year, according to BLS data for May 2025. Half of registered nurses in Mississippi earn more and half earn less.

Is Mississippi a high-paying state for registered nurses?

Mississippi ranks 50th of 51 states on median pay for this job. The national median is $97,550, so Mississippi pays 21% below it. The highest median is $140,270 in California.

How many registered nurses work in Mississippi?

BLS counted 29,060 registered nurses employed in Mississippi in May 2025.

Why is the average different from the median?

The median is the middle wage: half of workers earn less. The average adds every wage and divides, so a few very high earners pull it up. In Mississippi the average is $78,950, $1,860 above the median.

What do you need to work as a registered nurse in Mississippi?

Mississippi requires an associate or bachelor’s degree in nursing and a passing NCLEX-RN score, and a state license.